Sedatives, such as diazepam (Valium) Opioid medications affect your brain and may make you sleepy. FOOD LION PHARMACY. It is aimed for use in patients with difficulties initiating sleep. AUSTEDO. Zolpidem should usually not be taken for more than 7 to 10. Zolpidem is a sleeping pill that’s routinely prescribed for the short-term treatment of insomnia. Do not take with or right after a meal. These have included rage reactions, worsened insomnia, confusion, agitation, hallucinations and other forms of unwanted behaviour. These medications may be counterfeit and potentially unsafe. 75 and 3. pale skin. Apo-Zolpidem ODT was administered to rats and mice over a span of 2 years at dietary dosages of 4, 18, and 80 mg/kg/day. It belongs to a group of medications called hypnotic benzodiazepine receptor agonists, or HBRAs (sometimes called z-hypnotics or z-drugs). The way to take this medicine is: Oral. As extended release tab: 6. Older adults—5 mg or 1 spray into the mouth at bedtime. It's only used for a short period because your body gets used to it quickly. 2 hours after a dose on day 1 postpartum. For drugs that are used to treat sleeping disorders, the time to reach the maximum concentration (T max) of the drug in plasma is. Though it helps many people, this medication. Results: A total of 107 patients met the eligibility criteria. Zolpidem tartrate is a non-benzodiazepine hypnotic of the imidazopyridine class and is available in 5 mg and 10 mg strength tablets for oral administration. 75 to 2. No statistically significant differences were observed for Cmax, Tmax, half-life, and AUC between the first and last day of drug administration when baseline concentration. It may also. Adult: As immediate release tab: 5-10 mg immediately before bedtime. This medicine is taken by mouth. Mood swings. It makes you feel dizzy next morning. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. longer or heavier menstrual periods. IR TABLETS, ORAL SPRAY, and SUBLINGUAL TABLETS (5 and 10 mg formulations): 5 mg orally once a day immediately prior to bedtime-Maximum dose: 5 mg/day CR/ER TABLETS: Patients 65 years and over: 6. Max duration of treatment: 4 wk including tapering. Warning. zolpidem zolpidem ext-rel . 2 In the. location_on boydton, VA. Get Directions. Zolpidem is used for a short time to treat a certain sleep problem (insomnia) in adults. Ambien has also been associated with complex or dangerous sleep-related behaviors. Também não deve ser. On the other hand, zolpidem (Ambien) comes as short- and long-acting pills. Zolpidem, a nonbenzodiazepine hypnotic, binds to the benzodiazepine binding site on the gamma-aminobutyric acid type A (GABA-A) receptors. Ambien is an immediate release formulation of zolpidem. The 12. Store in Original Container. It helps you return to sleep faster so you can get a better night's rest. 7. The half-life of a drug is the amount. APO ZOLPIDEM ODT, 5MG, S/L TABLET Common uses. 25 mg and 12. noun. Get Ambien CR for as low as $18. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. AMBIEN CR 6. 2. Zolpidem Tartrate Tablet, 10 mg. Expert advice for Zolpidem. Main outcome was the presence of DILI measured as elevation of ALT/AST levels >250 U/l. Zolpidem Tartrate Tablets is available in 5 mg and 10 mg strength tablets for oral administration. 25. But only mild symptoms were observed in acute single-drug poisonings with zolpidem up to 0. But more information is needed to understand the potential role Ambien plays in. com. Observed reactions to zolpidem tartrate–containing products include anaphylaxis and angioedema [see. These common side effects of zolpidem happen in more than 1 in 100 people. Maximum dose: 1. Not violent, just dark and unpleasant, flipping from scene to scene. CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, difficulty staying awake. It also discusses the potential risks and benefits of using zolpidem for sleep disorders in pregnancy. That will purchase 30, 10 mg tablets, or one tablet per night at the highest dose. The recommended adult dose of zolpidem conventional tablets or spray is 5 mg for females, the elderly, or fragile individuals, and 5 to 10 mg for males. aching, high blood pressure, drowsiness. N05CF02 ZOLPIDEM Active ingredient group (AIG) number: See footnote 5. The standard oral dose is 10 mg taken at bedtime, even though a lower. Children—Use is not recommended. Maximum dose: 3. Next-morning sleepiness and alertness were not different between nights. This medication is typically used only once a day. 75 mg or 3. 25 mg, zaleplon (Sonata) 5 mg*, ramelteon (Rozerem) 8 mg, eszopiclone (Lunesta) 1 mg* for difficulty falling asleep, 2 mg for difficulty staying asleep 15,19,32 *Initial dose Long-acting benzodiazepines (B, C) (See entry under Anxiolytics) See entry under Anxiolytics. Schizophrenia can cause symptoms such as hallucinations (e. 0122857002. IT 117 Pill - pink round. The extended-release preparation treats both delayed sleep onset and decreased sleep latency. com. If any of these become troublesome, speak with your doctor. Therefore, the recommended APO-ZOLPIDEM ODT dosage is 5 mg once daily immediately before bedtime in this patient population (see DOSAGE AND ADMINISTRATION, Geriatrics). pain or tenderness around the eyes and cheekbones. Given the higher blood levels of Zolpidem Tartrate in women compared to men at a given dose, the recommended initial dose of Zolpidem Tartrate Tablets for adult women is 5 mg, and the recommended dose for adult men is 5 or 10 mg. Zolpidem: learn about side effects, dosage, special precautions, and more on MedlinePlus. Overall, zolpidem purportedly has fewer instances of abuse and dependence than traditionally used benzodiazepines. Drug Name Generic Name : zolpidem tartrate Brand Name: Ambien, Ambien CR Classification: Sedative or hypnotic (nonbarbiturate) Pregnancy Category B (immediate-release) Pregnancy Category C (extended-release) Controlled Substance C-IV Dosage & Route Available forms :Tablets—5, 10 mg; ER tablets—6. Zolpidem is a non-benzodiazepine hypnotic that acts by binding to (GABAA) receptor. Blister pack (Aluminium silver foil) of 7 or 14 tablets (AUST R 127151). The lower dose is recommended for the same groups of people as. It is not known if zolpidem tartrate is safe. Zolpidem Tartrate Extended Release. If the 5 mg dose is not effective, the dose can be increased to 10 mg. Common Ambien side effects may include: daytime drowsiness, dizziness, weakness, feeling "drugged" or light-headed; tired feeling, loss of coordination; stuffy nose, dry mouth, nose or throat irritation; Zolpidem is also available as an oral spray, which is sprayed into the mouth over the tongue, and a sublingual tablet to place under the tongue. Buy Ambien (Zolpidem) Online Without Prescription Contraindications and limitations to the use of Ambien zolpidem Hypersensitivity, the age to 15 years. Each metered actuation of Zolpimist delivers 5 mg of zolpidem tartrate in 100 μL. However, your pharmacist may have suggested a different schedule that is more appropriate for you. The recommended initial dose of APO-ZOLPIDEM ODT for adult women is 5 mg, and the recommended dose for adult men is 5 or 10 mg. Zolpidem parece tener efectos residuales mínimos. 25-12. com. Вообичаена доза: 10 mg непосредно пред спиење, по потреба дозата може да се зголеми на 15 mg на ден (max. Possui eficácia semelhante aos benzodiazepínicos no tratamento dos distúrbios do sono, possui um rápido inicio de atividade associado a uma modesta. Use the lowest effective dose for the patient. Insomnia. 30 Tablets. eletriptan ergotamine-caffeine naratriptan rizatriptan sumatriptan zolmitriptan . Parameters of sleep continuity, sleep architecture and cyclical structure of sleep were studied. Sleep walking, driving motor vehicles and other unusual and on. Zolpidem has an average rating of 6. Le zolpidem peut aider les personnes qui éprouvent de la difficulté à s'endormir et celles qui s'éveillent fréquemment pendant la nuit ou tôt le matin. Reaches peak concentration in the blood around 1. 6 hours postdose; a terminal elimination half-line of 1. Your body can also become. 5 mg tablets are blue, round, bi-convex, and debossed with A~ on one side. Rest assured that all zolpidem products are zolpidem tartrate. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. Common Ambien (zolpidem) side effects include daytime drowsiness, dizziness, and nausea. Warning. Zolpidem 10 mg showed a hypnotic effect on poor sleepers. Zolpidem is classified as a non-benzodiazepine hypnotic medication. Zopiclone has an average rating of 8. Sleep initiation. pale skin. AMBIEN 10 mg tablets are capsule-shaped, white, film coated, with AMB 10 debossed on one side and 5421 on the other. The pathways of zolpidem have several clinical implications since the agent affects sedation, electroencephalographic activity, oxidative metabolites and receptors in the central nervous system. Oral administration of zolpidem to pregnant rats from day 15 of gestation through lactation at 4, 20, and 100 mg base/kg/day, which are approximately 4, 20, and 100 times the MRHD of 12. This medication is typically used to help induce sleep. Oral administration of zolpidem to pregnant rats from day 15 of gestation through lactation at 4, 20, and 100 mg base/kg/day, which are approximately 4, 20, and 100 times the MRHD of 12. View chapter Explore book. 5 mg PO qHS; not to exceed 12. Its overall tolerability is favourable when administered according to the manufacturer's. Max: 12. pms-Zolpidem ODT: Zolpidem belongs to the class of medications called sedative-hypnotics. How to use this medication. This medicine is taken by mouth. Previous Next. 25 milligrams (mg) (for women) or 6. Zolpidem is used to treat people with sleeping difficulties (insomnia). This medication should be taken just before bedtime when required to help with sleep disturbances. However, the FDA has recommended using a 5 mg dose (6. 81. El zolpidem puede desarrollar adicción. Accordingly, the recommended dose of zolpidem for women has been reduced from 10 mg to 5 mg for immediate-release products (Ambien, Edluar, and Zolpimist) and from 12. Drowsiness or dizziness may last longer in older adults. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7–8 hours remaining before the planned time of awakening. Do not take this medicine (zolpidem tablets) unless you can get a full night's sleep (at least 7 to 8 hours) before you need to be active again. Middle-of-the-night awakening Use another zolpidem immediate-release product for 5 mg or 10 mg dosage. Of the total drug interactions, 28 are major, 424 are moderate, and 3 are minor. The randomized trials only showed convincing evidence of efficacy of 10 mg zolpidem. Zolpidem should usually not be taken for more than 7 to 10 consecutive. You could go into a very deep sleep, where you have difficulty waking up. Hallucinations, feeling irritable, nightmares, poor memory, throat and chest infections. The name of your medicine is APO - Zolpidem. Zolpidem was approved for use in the United States in 1992 for the short term treatment of insomnia and is the most commonly prescribed medication for insomnia with more than 10 million prescriptions filled yearly. 2) Dosage in Adults. Maximum dose: 12. Zolpidem tartrate is a sedative-hypnotic (sleep) medicine. APO ZOLPIDEM ODT, 5MG, S/L TABLET Common uses. The active ingredient (Zolpidem) is in the same amount. COMMON BRAND NAME (S): Ambien. 5 mg of zolpidem tartrate for oral administration. 25-12. longer or heavier menstrual periods. Medical Subject HeadingsThe recommended adult dose of zolpidem conventional tablets or spray is 5 mg for females, the elderly, or fragile individuals, and 5 to 10 mg for males. Shelf lifetime is 2 Years. It belongs to a family of substances colloquially known as "Z-drugs", which includes zaleplon (Sonata) and zolpidem (Ambien and AmbienCR). Store below 30 degrees Celsius. EU2EU: SPECIAL PHARMACY - 30% bonus pills for all reorders. lack of feeling or emotion. In regard to you feeling different effects with different manufacturers, this isn't overly common but it isn't unheard of. 5 mg almost every night has improved my life! I can get a solid 7-8 hours sleep regularly. Page 6 of 45 Clinical experience with zolpidem tartrate in patients with concomitant systemic illness is limited. 5 mg strength. Oral spray: Schedule IV. It is often used for a short period of time. more. Patients mainly. Chemically, zolpidem is N,N,6-trimethyl-2-p-tolylimidazo [1,2-a] pyridine-3-acetamide L- (+)-tartrate (2:1). 5 mg/day. 25, 12. Forms: 10 mg tablets or capsules. Ambien (zolpidem) for Insomnia "Awesome! 2. Use another zolpidem immediate-release product for 5 mg or 10 mg dosage. Instructions. Some people may also experience impairment in thinking and judgment. 5 mg (for men) once a day at bedtime. Benztropine (Cogentin) iii. 2)Zolpidem is a sedative-hypnotic medication (causes calm and sleep) that has been used to treat insomnia (not being able to fall asleep or stay asleep). 25 mg dose for Ambien CR) as the starting dose because of the risk of drowsiness the next day after taking a dose. 5 mg ER PO qhs; Info: use lowest effective dose, shortest possible tx duration; give immediately before bedtime and >7h before planned awakening; give 5 mg PO qhs or 6. Learn more about Zolpidem (Ambien) at EverydayHealth. 8%) showed DILI criteria. 5 mg tablets. Its effects can be felt within a few minutes. This medication is most effective when taken shortly before. 25mg and 12. : a sedative and hypnotic drug administered orally in the form of its tartrate (C19H21N3O)2·C4H6O6 in the short-term treatment of insomnia. numbness of the feet, hands, and around the mouth. Amantadine (Symmetrel) v. Rarely, this has led to severe injuries or death. Tell your doctor or pharmacist right away if you have withdrawal. Uses. Back pain. A comparative, randomized controlled trial of zolpidem and haloperidol in pediatric burn patients (n=40, mean age: 9. It is not known if zolpidem tartrate is safe and effective in. Most of the time people do not remember doing these things. 25mg in elderly patients). 60% of reviewers reported a positive effect, while 23% reported a negative effect. 12. BELSOMRA DAYVIGO QUVIVIQ . zolpidem; zopiclone; If you are taking any of these medications, speak with. Health care professionals should not prescribe eszopiclone, zaleplon, or zolpidem to patients who have a history of complex sleep behavior after taking these insomnia medicines. nausea. It helps you to get to sleep faster and stay asleep throughout the night. zolpidem compared to men. pale skin. (321) 343-3154. light-colored stools. They may cause side effects such as dizziness, headache, nausea and daytime drowsiness. Tablets are not scored. Zolpidem’s EC 50 on γ2 receptors was 230 nM and alpidem’s 500 nM. Sleep initiation. poor insight and. Only take one dose a day as needed for sleep immediately before bedtime; the recommended dose is 6. The reason that Zolpidem tartrate promotes longer periods of sleep than Zolpidem involves a drug’s half-life. Case reports and popular media suggest potential dangers exist and may result in unanticipated complications. Zolpidem is used to treat people with sleeping difficulties (insomnia). In addition, since the brain is the major organ involved, many investigations have been devoted to electrochemical action. poor insight and judgment. Most of the time people do not remember doing these things. 5 mg strength. Zolpidem Tartrate Strength 10 mg Imprint APO 10 Color White Shape Oval View details. Getty Images. 5 mg/spray (Zolpimist) Dosage Considerations – Should be Given as Follows: Not recommended for pediatric use. Get free Zolpidem coupons instantly and save up to 80%. 2. Quantity: 30-300 pills. 5 mg daily for up to 4 weeks, dose to be taken at bedtime. 25 or 12. Ambien side effectsA randomized double-blind crossover interaction study in twelve healthy subjects showed that co-administration of a single 5 mg dose of zolpidem tartrate with ketoconazole, a potent CYP3A4 inhibitor, given as 200 mg twice daily for 2 days increased C max of zolpidem by a factor of 1. Diphenhydramine (Benedryl) iv. Strengths: 5 mg, 10 mg; Brand: Ambien CR. Some people taking this drug have done things like sleepwalking, sleep driving, making and eating food, having sex, or other actions while not fully awake. 1 / 3. In contrast to the benzodiazepines, which non-selectively bind to and. Zolpidem parece tener efectos residuales mínimos. 5 mg dose, always look for the embossed “A~” on your round pill. This medication is typically used to help induce sleep. loss of memory. Sin embargo, se presentó evidencia subjetiva de alteración del sueño en los pacientes ancianos que recibieron dosis superiores a 5 mg. It works by acting on your brain to help you sleep. In the past two decades, many studies have shown the paradoxical efficacy of zolpidem, a hypnotic used to induce sleep, in transiently alleviating various disorders of consciousness such as traumatic brain injury (TBI), dystonia, and Parkinson's disease. tender, swollen glands in the neck. Maintenance dose: 6. It is often used for a short period of time. Check out the AMBIEN CR pill images to help make sure you have the AMBIEN CR brand. Zolpidem 5 mg once a day → 10 mg in the morning and 5 mg in the evening → 10 mg twice/d, Time to response: 1 h Duration of response: 3-6 h depending on dosing: Zolpidem 5 mg once a day: Increased arousal and more interactive with caregivers. Children—Use and dose must be determined by your doctor. Your body can also become. 3 out of 10 from a total of 1400 ratings on Drugs. Dizziness or severe drowsiness can cause falls, accidents, or severe injuries. . Interchangeables found: 4: New Search: DIN/ PIN/ NPN Brand Name Drug Benefit Price or Unit Price Amount MOH Pays: 02436159: Apo-Zolpidem ODT (Off-Formulary Interchangeable) 1. light-colored stools. 25 to 12. Zolpidem belongs to a class of drugs called sedative-hypnotics. 1 It is used for sedation, anxiety reduction, and central muscle relaxation, and it has an anticonvulsant effect. 25 mg or 12. Feeling dizzy. driving, or operating machinery); effects of alcohol and other CNS depressants enhanced. 5 mg/day Dosing considerations (Ambien, Ambien CR) Use lowest effective dose; take only once per night immediately before bedtime with at least 7-8. It also discusses the potential risks and benefits of using zolpidem for sleep disorders in pregnancy. 5 mg of zolpidem tartrate for oral administration. Zolpidem may cause serious or possibly life-threatening sleep behaviors. They can lead to more drowsiness, dizziness, and even cause trouble breathing. Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992. How to use this. Optimal therapy can aid patients in returning to baseline and increase their quality of life. Background and purpose: Zolpidem, a short-acting hypnotic drug prescribed to treat insomnia, has been clinically associated with acquired long QT syndrome (LQTS) and torsade de pointes (TdP) tachyarrhythmia. Yes: Yes, these may be safely taken together as long as it is under the supervision of a physician and they are being taken as prescribed. seeing double. 99 CAD/month to see the product description. (3) Protein-binding affinity: a high proportion of zolpidem is protein bound. Take only 1 dose a night as needed. USES: Zolpidem is used to treat sleep problems (insomnia) in adults. BELSOMRA DAYVIGO QUVIVIQ . Zolpidem may also interact with some antidepressants. Results: The elderly and female patients were prescribed significantly lower doses of zolpidem than their counterparts. Neither compound showed robust efficacy on γ1 containing receptors. The maximum dose. Liver enzymes alterations were present in 9. Form: sublingual tablet; Strengths: 5. Do not suddenly stop taking zolpidem without medical advice. Rationale: Zolpidem is a short-acting, non-benzodiazepine hypnotic that acts as a full agonist at α1-containing GABAA receptors. Zolpidem Tartrate Tablets 10 mg is white film coated, round biconvex tab lets, debossed. DIN/PIN/NPN: 02436159. Zolpidem is used in the treatment of Insomnia and belongs to the drug class miscellaneous anxiolytics, sedatives and hypnotics. Eszopiclone or zolpidem extended release can be utilized for both sleep onset and sleep maintenance. You'll usually take it for a few days or weeks (up to 4 weeks). The rate of congenital abnormalities was not significantly increased with zolpidem (0. During withdrawal of zolpidem, there was a decrease in body weight, food intake, relative food intake, and anxiety, as well as a negative feed efficiency. Use another zolpidem immediate-release product for 5 mg or 10 mg. Take this medicine (zolpidem tablets) only 1 time per night. Back pain. 1827: N/A: 02436175:Uses. AJOVY EMGALITY NURTEC ODT. It interacts with a GABA-BZ receptor complex and shares some of the pharmacological properties of the benzodiazepines. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7-8 hours. nate. Individuals can begin experiencing dangerous. O zolpidem não deve ser usado em pessoas com alergia à substância ativa ou a qualquer componente presente na fórmula. For the treatment of insomnia (trouble sleeping): For oral dosage form (oral spray): Adults—10 milligrams (mg) or 2 sprays into the mouth at bedtime. eletriptan naratriptan rizatriptan sumatriptan zolmitriptan . 5 to 6. If you have trouble falling asleep, it helps you fall asleep faster, so you can get a better night's rest. AMBIEN CR 12. Study with Quizlet and memorize flashcards containing terms like Withdrawal from long-term use of sedative-hypnotic drugs is characterized by A. 1827: N/A: 02436175:Exclusion criteria: missing lab data; lack of informed consent. 5 mg; Brand: Edluar. 5 mL/min) undergoing hemodialysis three times a week, who were dosed with zolpidem tartrate 10 mg orally each day for 14 or 21 days. 75 mg/day. Zolpidem belongs to the class of medications called sedative-hypnotics. This book chapter reviews the pharmacology, pharmacokinetics, and clinical studies of zolpidem in pregnant women and their fetuses. Feeling or being sick (nausea or vomiting) Diarrhoea. “Ambien is really only indicated for insomnia sleep onset and not for maintaining. Refer to product labeling for detailed information , . loss of memory. Max: 10 mg/day. , Suite 100 Montréal, Québec H4P 2T4 Date d’approbation initiale: 07 decembre 2016 Date de révision :Zolpidem is a sedative and a hypnotic substance that is used to treat insomnia and difficulty sleeping. If you have trouble falling asleep, it helps you fall asleep faster, so you can get a better night's rest. Zolpidem must not be used for more than 4 weeks at a time. Methods: Twelve participants with OSA received 10 mg zolpidem plus Ato-Oxy (80-5 mg, respectively) or Ato-Oxy plus placebo prior to overnight in-laboratory PSG according to a double-blind, randomized, crossover design (1-week washout). The recommended dose of AMBIEN in these patients is 5 mg once daily immediately before bedtimeObjective: The Z-drugs (zolpidem, zopiclone, zaleplon) are widely used to treat insomnia in patients receiving prescription opioids, and the risk of overdose resulting from this coprescription has not been explored. It’s important for a therapy plan to be. 25 mg tablets are pink, round, bi-convex, and debossed with A~ on one side. Pharmacology, Pharmacokinetics and Pharmacodynamics. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7–8 hours remaining before the planned time of awakening. Form: extended-release oral tablet; Strengths: 6. 8% of whom were urban. The recommended initial doses for women and men are different because zolpidem clearance is lower in women. Zolpidem tartrate tablets are available in 5 mg and 10 mg strength tablets for oral administration. The health benefits of this can not be underestimated! Ambien in not addictive. INTRODUCTION. IT 118. 5 mg―should not drive or participate in other activities requiring full mental alertness the day after taking the drug, due to the fact that zolpidem concentrations can remain increased the next day, and impair the. Zolpidem systemic is used in the treatment of: Insomnia; Chemical structureAPO ZOLPIDEM ODT, 5MG, S/L TABLET Common uses. Learn what Ambien (zolpidem) is, how it works to treat insomnia, potential side effects, the proper dosage, and what safety precautions are important. lack of feeling or emotion. This book chapter reviews the pharmacology, pharmacokinetics, and clinical studies of zolpidem in pregnant women and their fetuses. Print patient leaflet as text only. MeSH. Zolpidem 10 mg/day and zopiclone 7. T\CZOLPIDEM TARTRATE ODT Zolpidem tartrate sublingual orally disintegrating tablets 5 mg and 10 mg PART I: HEALTH PROFESSIONAL INFORMATION SUMMARY PRODUCT INFORMATION Route of Administration Dosage Form / Strength Nonmedicinal Ingredients Oral/sublingual Orally Disintegrating Tablet (ODT) 5 mg, 10 mg Colloidal Silicon Dioxide, Croscarmellose Stomach upset (such as diarrhoea, feeling sick (nausea), or abdominal discomfort) Stick to simple meals - avoid rich or spicy meals. Zolpidem is used for a short time to treat a certain sleep problem (insomnia) in adults. LQTS is primarily attributed to reduction of cardiac human ether-a-go-go-related gene (hERG)/I(Kr) currents.